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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e0bdae74d7e4db66564e720bb16b202a8672a3010c9401fe523d7cbc650848c' 
  AND token = '2KS5dluQEbhVjr0c8i3B3SVZIWwcQrHMUWrMPK3TtlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}