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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d6372f93060d3c801af3176c8793d5be703959a939df66cb4a21c2cebce27c' 
  AND token = 'u0ZP0jSv+gwSv9LLps72ml/LGljqWla2J0QZvncgE6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}