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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526619c0cb96c81ce0264a0d32d93e2fe6db35ab025f071047793cba42826692' 
  AND token = '6JNiNAnYNuCZ/UxXAWYBYaXKBPDG5bAwQkyp+bAK5ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}