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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af7ef1775bc39dd1e6d7e33894719c904844205363bc65154f2d15a1f354b50d' 
  AND token = 'p7rmrpWW8oR2JLYH2nkxSK9o1gyqdwnOP635ywPgzw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}