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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8c5b4285e16ad1cef9403448beeb401ecea159e7153e6ed177e0da1e200495' 
  AND token = 'ike9yMVA/HXVKEZF/RnaU2j9MQFWqPq8DovrZLc1e/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}