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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861dd8ffb73780460db01580a3b327669f13d38445339e04f7b63d3e2ac39f13' 
  AND token = 'rEz2M//rNxWOk0Z4l+PCZm6N3aezUwcWaIftowKOnUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}