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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65f506d47c54f976008044215e134590a2a28ea52399603d259787a7db3ea1a' 
  AND token = '7cRomQvn44NMug/OKnF5cYQTS14fGNAlRVG2S8+Mx9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}