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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86cba40f21a205557fc349a4c017b3f65ffbf4471c11828f4676ca74c242c067' 
  AND token = '2T06OPmiW9jdBvBV+nQEGwEt44NGf7pSKawRCNBI13w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}