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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35516891ecef0c3eb59663081ff8cf3c109505f8e0262ff390354010d19dc80d' 
  AND token = 'DEj7dng5on+2zGp6EQ2X2HOsWGGSLvfQaNzyjoPk4s8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}