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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7646fd4abf14b3e2c639f94d16eac0a00f48dee00c858b701e409d1183b15df7' 
  AND token = 'fBeyXWBHqYeITw1IJoa1Oi8XwMTMUM2iJks2Jg4BhnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}