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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56f7022c1bce5dbbafbc233618e0b6e0757fd93df7c2e03f35924368c3375a0e' 
  AND token = 'HJ6xKQR/JxDNfcih67Mr1yI3F3B7VQcTpxP/qCmzZfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}