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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4033f4d062338021de773048b88fcdd254b7186db890202d32833766fb3cfe32' 
  AND token = '1zRAcYeW139XgOX5VpXHowDLmyQ32qZexiym0RgOhjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}