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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '542d6290ab1b84e39092e5f4cf762b7182a61126c8d1029f3265cdd011c026ec' 
  AND token = 'EvPlB+FcXR1Dg8jgWO8Xbemg7BdhbzU7BALrMGyzSd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}