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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71eb7645d8bdb238f2920e88e48a0b8acaa42a948a11ea038daebf9ab5a5e82c' 
  AND token = 'j5PGpPjF874Uq6C3lYcVsvHUNSiT+rSGfjBIS6aP/H8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}