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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80169bf5d2cac4567c92ada475923cf894db3c21991f02ba0ed03e3bc750555a' 
  AND token = 'tUJBbYg13crCD2EUyfI2UwbuH8iIo5B7k29MpVJbsqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}