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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e289ab7be2a28af57328357f1aa63788e892b408544af50bc16b23e2a78b5e23' 
  AND token = 'w9L3ndEtr4PQpheG+NCKslzwznkOsIIPYY9uOMFCu18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}