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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c73fb41a7dad92580432e6806991d30de7d2a3add20c160521436186262445c6' 
  AND token = 'gjb0SIiBy7IxVLcwo4xtPXanX0eFb6JwarXnAbwsY4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}