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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4344763829955c09da2ecade3a88289f5a7f5d21641cf803b98578d7e19cae2' 
  AND token = 'ZFVuN+QM9028u/WRxKwcHfr1BGdZ9ASZ15kroLXYsoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}