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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a80a43d2a44928e959948fd7e2010941342680f0875d484cf8fd6b4ad533020d' 
  AND token = '5/PZ9E0yHMrpbp/d2961zhIJ6RONQ/9uFTlIkb2A5fo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}