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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '121b5904bc13fd6e08d247d4c4b05809c1df68fbcf81d941d36253a6f2cf22e8' 
  AND token = 'TkXIai78cva7/KaoHk0c0U4nl3/WS5hwkreSvWbhGEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}