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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e25fe7a4f7870feabb67cb777d3cde87fcb641c21854ed9bec73ad512a92d4c1' 
  AND token = 'jIjh4sY+p3Zi6Q0ty4250sZ6ldsTrUVAb5j/71gMqBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}