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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca4b9c4f81483d1b4e61bbfffa4c6a1b228fb58d1565658eca2173e10726d609' 
  AND token = 'ZCl0+/CEhibmzwIs4Bjr8meRJr9uPHSeEla8OMwdWU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}