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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a88a5139b5e59cd23bab387d6d7c83d527de1d5dca7490f9ee2f034c17c9d47f' 
  AND token = 'Kmc6mBy9c97X8NAF83kOkb1NV7qx8OJvroxOSFTdG+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}