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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af6ac24f2bd78c143ca31c54e8bac28b7d945ae6648f889874623fa2aae86b17' 
  AND token = 'IbPqKgZ1EI6UgQUvB+JqH2L5Mr0U+KMAFNRtmgKKltg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}