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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2295a3e81f11a398196297d52f45c31f973b364f193e3915b716ff195d622fda' 
  AND token = '8Q9QgmQoQTOW5KM7b+qwNawekRkc0DLsAHAzpxrA+uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}