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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6350d4328d59d9131cdb6ad9e16d2da26205e25ffb99b7d6fbade64b47b7f066' 
  AND token = 'S3fSOt3onNA2IxIygCykfs994cvprp31Gl6sh6J5ZkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}