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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211218fd941e113bb2d1fead316d61e975b04b7215dbe434cdacf1726d86b471' 
  AND token = 'x09Rf3WUIJNgT6RiuT/yuAGa3TRcNMh9nKyBEBG4RV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}