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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d253100f796322f8d476918da9949d21ac3ca711cc15c88c1318d828c91649b' 
  AND token = 'Q5LFq2dNx4HOdvdhnc00vPRiAdZB+07QzSQtNbbO2/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}