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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d61895a222fc492c5aba42ab1a234b4c940b781602e9b0b1502681e40e387c1' 
  AND token = 'Nj821IR/6B9i6AWxGCqdAsMZZCo3nwLysZEctSh4JkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}