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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc59492e3bd5455fbf827a3c158273912ec8fc85eb384887ac323c806dea6e1' 
  AND token = 'nLFTjTAME5pbpzgIpo0Y4eENRN4ADwDrB1XPM8CsPOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}