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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b340c0484ced4dd856e8306e70bde59e7ea88c99d03dd2bf34666f40b038b9cb' 
  AND token = 'wH+R/WUqOAxq/sfRs6iRF/vffqvqyJd/zPnwLG+/4zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}