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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a252c78b20eb945339b10baa2d85fe957ee8fcbd8d930e3348961c8df44a61ca' 
  AND token = 'uwPAQZDUkknL6oAW/51fGZ1Q6lY4G0MWPTM3TdDLfwU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}