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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7bbaf5cb2da2e3bb64611485f2ff114067c2e56ddcac715a1ed2bd05523b63' 
  AND token = 'KS0+Kt/EpbXFuTYYwgcO3n0mHdDLFlxawmtKnoFe6PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}