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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a1ee35fbdb0d66d9120a2790bbcd6483243f1577a85935348ae918c11e9d5f' 
  AND token = 'k6Nj9sEph5TTE+RyXDKm/png8Gu84Zri2pedMy8e2tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}