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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d82ee6bb26f9e876a66e62250be7c8cfc9b99782cca7edec91477957ee1e73' 
  AND token = 'tHY3HMjhdLegCSZlqXlejwOsEW5jUg2f6eCR28oGcqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}