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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ef95d00e7c8d501caeb8fc6347914014bdcb9d2f3e91d63f785b919f906d558' 
  AND token = 'MjLIkjVe2Yu7EikXB2VAbOGulBa0NQ3Pm+pZMOWeH8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}