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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7246d57440419f3e99e73e87e34b3e363f4a9a6ddcf0c54c7504a6ca11018f14' 
  AND token = '+f3U/Rtk1L5i2SyVLqW5RsOq+w6U7YTMlDaYEUQpku4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}