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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1504075e24cdb454f36fe82fbd37f04d3f301c2394338a47fccc43e3e8a22e6' 
  AND token = 'CQw4CJ2jEOXE+h+8Qrh6524RnKFf86n5LFv7F1g5jvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}