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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad4abcb7d4a83dd3f99cf9e449666b85b89a5683f9a7ecface0827e914feb6d2' 
  AND token = 'RqN9ixIMUya1V7HMR8KyOc37Sbuk6ZBSgmM/pOdGWtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}