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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9483d0a476f30b521fec04140fd30ea4290c237a97c9c99109ba1df7a0d76eb8' 
  AND token = '0PGPKCKRI1uzQ4mPpKkTiDzMAuwI3ed+zXlkpJWwQ/k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}