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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2a4047e51e6668dbc1db33d12a5b741a2365cee4aad2d9e23b9964b7311a89' 
  AND token = 'SElqZhqC3fG6RoxwvyE+DAsdxHGcPi3BAe1fb5ikHt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}