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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ed65ede590cfac1a5415ddf7075f9cd0cb5c8d37a8cb52efa77b4706654b47d' 
  AND token = 'r9GxLhLq4CtdlqR5hPODuo17AhbJvrxU2JtjPT03yDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}