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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4f05300e75c8f73686ff94c789c17f750bc8d54bfe0166498bf81b5695f6ac5' 
  AND token = '4nfKVe99w4ZBMmw8HfLL4sZUcS0fpa9COwmQ1XugUWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}