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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe9ba5006f2a0cfe233d6b1e7c8df3c69035373ceed0a746d9368bf070e7c53' 
  AND token = 'adEVT6xulxPx+D4fd3/m/wN3VI0L5EKXhBhPtW4aU9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}