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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e50103c48fd9e5e7d13c1324cdeb26531bc662995d3c58601c1aeff5c939f1a' 
  AND token = 'xCmMEWKRTloIIOnpp6C3iQYJeUzL50c4d3TtkZKnKXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}