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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6c7a5d8d2e7f8baeda9d3ff1c4014dd511797d086c9990a1bd3ba86fee5225' 
  AND token = 'LCF8+ICH1rouCYcoi8CaYLfO6i8/xbIrIYMvsHe/uNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}