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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0152b70fffc8dd9a0be5d4e4b8209e89cac44d6c38256edf57940092c57cb4fb' 
  AND token = 'vxTdfWMWMghBuBrhTmjust5Lk06M+9EIhix7Ttcoju8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}