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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363a99fcd4c9f1adabbfe4df06fbef3fb63ae451ec1a5be071546692ddaae454' 
  AND token = 'dhl2VZfZPly05icIAVoajR8vGkTwPcuQJ2PwTt5MWz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}