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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b18be58a4e03e77fa6c6719a7ab12ea1afed991f603212b69b08b383855dd8d' 
  AND token = 'BMmAtiMaUIlRBOyKBqEmpPZCULmgO83Tm5REW2re/p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}