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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66126d07eddb6092957e268b5206dc73f0100cff49e7298e69b91f3ce0cfc73d' 
  AND token = 'Nd97Ve6LqBdGdyqjd/8sGg6zcPcUTC4s/G8QK4z2K5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}